Formononetin (Biochanin B，刺芒柄花素)
> 100 μM
Compound: 13
Cytotoxicity against human A549 cells after 72 hrs by MTT assay
Cytotoxicity against human A549 cells after 72 hrs by MTT assay
[PMID: 18440233] A549 ED502.87 μg/mL
Compound: 11
Cytotoxicity against human A549 cells after 7 days
Cytotoxicity against human A549 cells after 7 days
[PMID: 8201311] B16-BL6 IC50> 100 μM
Compound: 13
Cytotoxicity against mouse B16-BL6 cells after 72 hrs by MTT assay
Cytotoxicity against mouse B16-BL6 cells after 72 hrs by MTT assay
[PMID: 18440233] BV-2 IC50> 100 μM
Compound: 19
Anti-neuroinflammatory activity against mouse BV2 cells assessed as inhibition of LPS-induced nitric oxide production after 24 hrs by Griess assay
Anti-neuroinflammatory activity against mouse BV2 cells assessed as inhibition of LPS-induced nitric oxide production after 24 hrs by Griess assay
[PMID: 25466192] BV-2 IC5013.19 μM
Compound: 2
Antineuroinflammatory activity in mouse BV2 cells assessed as inhibition of LPS-induced NO production after 24 hrs in presence of LPS by Griess reaction based assay
Antineuroinflammatory activity in mouse BV2 cells assessed as inhibition of LPS-induced NO production after 24 hrs in presence of LPS by Griess reaction based assay
[PMID: 28911817] DU-145 IC50> 100 μM
Compound: Formononetin
Cytotoxicity against human DU145 cells after 72 hrs by MTT assay
Cytotoxicity against human DU145 cells after 72 hrs by MTT assay
[PMID: 22633834] ECa-109 cell line IC50> 100 μM
Compound: 1
Cytotoxicity against human EC109 cells assessed as inhibition of cell viability after 48 hrs by MTT assay
Cytotoxicity against human EC109 cells assessed as inhibition of cell viability after 48 hrs by MTT assay
[PMID: 28038329] HCT-116 IC5060.97 μM
Compound: Formononetin
Cytotoxicity against human HCT116 cells after 72 hrs by MTT assay
Cytotoxicity against human HCT116 cells after 72 hrs by MTT assay
[PMID: 22633834] HeLa IC50> 100 μM
Compound: 13
Cytotoxicity against human HeLa cells after 72 hrs by MTT assay
Cytotoxicity against human HeLa cells after 72 hrs by MTT assay
[PMID: 18440233] HeLa IC508.51 μM
Compound: Formononetin
Cytotoxicity against human HeLa cells after 72 hrs by MTT assay
Cytotoxicity against human HeLa cells after 72 hrs by MTT assay
[PMID: 22633834] HepG2 IC5060.5 μM
Compound: 15
Anticancer activity against human HepG2 cells assessed as cell viability after 24 hrs by MTT assay
Anticancer activity against human HepG2 cells assessed as cell viability after 24 hrs by MTT assay
[PMID: 24974349] HT-1080 IC50> 100 μM
Compound: 13
Cytotoxicity against human HT1080 cells after 72 hrs by MTT assay
Cytotoxicity against human HT1080 cells after 72 hrs by MTT assay
[PMID: 18440233] HT-29 ED506.43 μg/mL
Compound: 11
Cytotoxicity against human HT-29 cells after 7 days
Cytotoxicity against human HT-29 cells after 7 days
[PMID: 8201311] Lewis lung carcinoma cell line IC50> 100 μM
Compound: 13
Cytotoxicity against mouse LLC cells after 72 hrs by MTT assay
Cytotoxicity against mouse LLC cells after 72 hrs by MTT assay
[PMID: 18440233] MCF7 ED501.96 μg/mL
Compound: 11
Cytotoxicity against human MCF7 cells after 7 days
Cytotoxicity against human MCF7 cells after 7 days
[PMID: 8201311] MDCK CC50123 μM
Compound: 3
Cytotoxicity against MDCK cells after 72 hrs
Cytotoxicity against MDCK cells after 72 hrs
[PMID: 24313801] MDCK IC5038.2 μM
Compound: 3
Antiviral activity against Influenza A virus J/8178/09 infected in MDCK cells assessed as inhibition of virus-induced cytopathic effect after 48 hrs
Antiviral activity against Influenza A virus J/8178/09 infected in MDCK cells assessed as inhibition of virus-induced cytopathic effect after 48 hrs
[PMID: 24313801] MDCK IC5042.6 μM
Compound: 3
Antiviral activity against Influenza A virus (A/Hong Kong/1/1968(H3N2)) infected in MDCK cells assessed as inhibition of virus-induced cytopathic effect after 48 hrs
Antiviral activity against Influenza A virus (A/Hong Kong/1/1968(H3N2)) infected in MDCK cells assessed as inhibition of virus-induced cytopathic effect after 48 hrs
[PMID: 24313801] MGC-803 IC50> 100 μM
Compound: 1
Cytotoxicity against human MGC803 cells assessed as inhibition of cell viability after 48 hrs by MTT assay
Cytotoxicity against human MGC803 cells assessed as inhibition of cell viability after 48 hrs by MTT assay
[PMID: 28038329] N9 IC50> 100 μM
Compound: 4
Antineuroinflammatory activity in mouse N9 cells assessed as inhibition of LPS-induced nitric oxide production after 24 hrs by Griess assay
Antineuroinflammatory activity in mouse N9 cells assessed as inhibition of LPS-induced nitric oxide production after 24 hrs by Griess assay
[PMID: 28073678] PC-3 IC5057.01 μM
Compound: 1
Cytotoxicity against human PC3 cells assessed as inhibition of cell viability after 48 hrs by MTT assay
Cytotoxicity against human PC3 cells assessed as inhibition of cell viability after 48 hrs by MTT assay
[PMID: 28038329] RAW264.7 IC5056.1 μM
Compound: 6
Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced nitric oxide production after 24 hrs by Griess assay
Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced nitric oxide production after 24 hrs by Griess assay
[PMID: 23743282] SGC-7901 IC502.17 μM
Compound: Formononetin
Cytotoxicity against human SGC7901 cells after 72 hrs by MTT assay
Cytotoxicity against human SGC7901 cells after 72 hrs by MTT assay
[PMID: 22633834] SH-SY5Y IC50> 100 μM
Compound: Formononetin
Cytotoxicity against human SH-SY5Y cells after 72 hrs by MTT assay
Cytotoxicity against human SH-SY5Y cells after 72 hrs by MTT assay
[PMID: 22633834] U-937 IC5044 μM
Compound: 6, formononetin
Antiproliferative activity against human U937 cells after 48 hrs by WST-8 assay
Antiproliferative activity against human U937 cells after 48 hrs by WST-8 assay
[PMID: 17158054] U-937 IC5045 μM
Compound: 6, formononetin
Antiproliferative activity against human U937 cells after 72 hrs by WST-8 assay
Antiproliferative activity against human U937 cells after 72 hrs by WST-8 assay
[PMID: 17158054] U-937 IC5050 μM
Compound: 6, formononetin
Antiproliferative activity against human U937 cells after 24 hrs by WST-8 assay
Antiproliferative activity against human U937 cells after 24 hrs by WST-8 assay
[PMID: 17158054]相关知识
刺芒柄花素
Formononetin (Biochanin B，刺芒柄花素)
刺芒柄花素在抗真菌药物中的用途
JNB：刺芒柄花素抑制宫颈癌的机制研究
研究称植物化合物刺芒柄花素显示出治疗食物过敏的前景
Research Progress of Formononetin for Anticancer Drug Development
刺芒柄花素防治炎症相关疾病的研究进展
刺芒柄花素的作用和临床应用
刺芒柄花素 一公斤起订兰州市
芒柄花黄素在抗真菌药物中的用途
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