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红花的黄酮类化学成分研究

花匠小妙招
2025-05-12 07:08

目的研究红花中的黄酮类成分。方法采用多种色谱方法对红花药材进行分离纯化，根据化合物的理化性质及其波谱数据进行结构鉴定。结果从红花药材中分离鉴定了10个黄酮类成分，分别为6-羟基槲皮素-3，6，7-三氧葡萄糖苷（1，6-羟基山柰酚-3，6-二氧-7-氧葡萄醛酸苷（2，6-羟基山柰酚-3，6，7-三氧葡萄糖苷（3，6-羟基山柰酚-3-氧葡萄糖苷（4，6-羟基山柰酚-3-氧芸香糖苷（5，6-羟基山柰酚-6，7-二氧葡萄糖苷（6，6-羟基芹菜素-6-氧葡萄糖-7-氧葡萄糖醛酸苷（7，6-羟基山柰酚-3，6-二氧葡萄糖苷（8， 6-羟基山柰酚-3-氧芸香糖-6-氧葡萄糖苷（9，(2S-4′，5-二羟基-6，7-二氧葡萄糖二氢黄酮苷（10。结论化合物1为新化合物。

Abstract

OBJECTIVE To study the flavonoids in the flower of Carthamus tinctorius L.. METHODS Multiple chromatographic methods were used for the isolation and purification. Structures were elucidated on the basis of spectroscopic data analysis. RESULTS Ten compounds were isolated and identified as 6-hydroxyquercetin 3，6，7- tri-O-β-D-glucoside(1，6-Hydroxykaempferol 3，6-di-O-β-D-glucoside-7-O-β-D-glucuronide(2，6-hydroxykaempferol 3，6，7-tri-O-β-D-glucoside(3， 6-hydroxy kaempferol 3-O-β-D-glucoside(4，6-hydroxykaempferol 3-O-β-D-rutinoside(5，6-hydroxykaempferol 6，7-di-O-β-D-glucoside(6，6-hydroxyapigenin 6-O-β-D- glucoside-7-O-β-D-glucuronide(7，6-hydroxykaempferol 3，6-di-O-β-D-glucoside(8， 6-hydroxykaempferol 3-O-β-rutinoside-6-O-β-D-glucoside(9，(2S-4′，5-dihydroxyl -6，7-di-O-β-D-glucopyranosyl flavanone(10. CONCLUSION Compound 1 is a new compound.

关键词

红花 /黄酮 /6-羟基槲皮素-3 /6 /7-三氧葡萄糖苷{{custom_keyword}} /

Key words

Carthamus tinctorius L. /flavonoids /6-hydroxyquercetin 3 /6 /7-tri-O-β-D-glucoside{{custom_keyword}} /

引用本文

导出引用

范莉赵海誉濮润韩健王宝荣果德安.红花的黄酮类化学成分研究[J]. 中国药学杂志, 2011, 46(5): 333-337

FN Li;ZHO Hi-yu;PU Run;HN Jin;WNG o-rong;GUO De-n.Study on Flavonoids in the Flower of Carthamus tinctorius L.[J]. Chinese Pharmaceutical Journal, 2011, 46(5): 333-337

参考文献

[1] Ch. P(2005 VolⅠ(中国药典2005 年版.一部 [S]. 2005：103-104.
[2] YANG Y，WU W，ZHENG Y L. Advances in studies on safflower(Carthamus tinctorius L. [J]. J Sichuan Agricu Univ （四川农业大学学报，2004，22(4：365-369.
[3] KAZUMA K，TAKAHASHI T， SATO K，et al. Quinochalcones and flavonoids from fresh florets in different cultivars of Carthamus tinctorius L. ［J］. Biosci Biotechnol Biochem，2000，64(8：1588-1599.
[4] REN S，YE Y，ZHAO W M. Natural Product Chemistry(天然产物化学［M］. Beijing：Sciene Press，2004：554.
[5] ESPERANZA J C G，LUMONADIO L，SANG K L，et al. Antioxidant flavonoid glycosides from daphniphyllum calycinuml［J］. J Nat Prod，1998，61（5：706-708
[6] LI F，HE Z S，YE Y. Flavonoids from Carthamus tinctorius［J］. Chin J Chem[中国化学（英文版]，2002，20(7：699-702.
[7] LI F，ZHAO H Y，XU M，et al. Qualitative evaluation and quantitative determination of 10 major active components in Carthamus tinctorius L. by high-performance liquid chromatography coupled with diode array detector［J］. J Chromatogra A，2009，1216(11：2063-2070.