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Research progress on the extraction, separation, and purification of chemical constituents from species

摘要

石斛素有“药中黄金”之称,历代医家视为中药之极品,多以茎入药,其含有多糖、生物碱、黄酮、联苄类、菲类、酚类、苯丙素、烯类、植物甾醇、氨基酸及微量元素和挥发油等。石斛的叶和花也含有多种化学成分,但其叶和花化学成分的分离和精制方法还不完善,严重影响了石斛深度全效利用开发。该研究查阅了近年来石斛属植物研究的大量文献,根据石斛茎、花及叶的特点,探讨了其有效成分和提取分离精制方法,为未来石斛属植物的综合利用开发及石斛属产业的可持续发展提供有力技术支撑。

关键词: 中草药;石斛属;花;叶子;植物提取物;化学技术,分析;综述

ABSTRACT

Dendrobium has long been referred to as the "gold in medicine" and is highly valued as a key component of traditional Chinese medicine. It is primarily the stems of Dendrobium that are used, containing a variety of compounds such as polysaccharides, alkaloids, flavonoids, bibenzyl analogs, phenolics, phenylpropanoids, alkenes, phytosterols, amino acids, trace elements, and volatile oils. Although the leaves and flowers of Dendrobium also contain numerous chemical constituents, the methods for separating and purifying these components are still not fully developed. This limitation has hindered the comprehensive utilization and development of Dendrobium. This review analyzes a substantial body of recent literature on Dendrobium species and explores their effective components, as well as the methods for extraction, separation, and purification of the stems, flowers, and leaves. Findings from this review help provide essential technical support for the comprehensive utilization of Dendrobium species and the future development of the Dendrobium industry.

KEYWORDS: Drugs, Chinese herbal;Dendrobium;Flowers;Cotyledon;Plant extracts;Chemistry techniques, analytical;Review

FUNDING:

Scientific Research Plan Project of Anhui Provincial Health Commission(AHWJ2021a018)

2022 Provincial-Level Quality Engineering Project for Higher Education Institutions in Anhui Province(2022 kcsz149)

Key Project of Natural Science Foundation for Higher Education Institutions in Anhui Province(2024AH050851)

COPYRIGHTS:

Copyright by Chinese Medical Association

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All articles published represent the opinions of the authors, and do not reflect the official policy of the Chinese Medical Association or the Editorial Board, unless this is clearly specified.

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