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芳香开窍中药对中枢神经系统疾病的治疗作用研究进展

花匠小妙招
2025-03-03 10:55

摘要: 通过对芳香开窍中药麝香、冰片、石菖蒲、苏合香、安息香和以这类中药为主的安宫牛黄丸、麝香保心丸和苏合香丸相关的药理作用进行总结，发现它们对缺血性脑卒中、阿尔茨海默病、抑郁症、癫痫和帕金森病等中枢神经系统疾病具有治疗作用，其主要是通过调节血脑屏障通透性、抑制炎性反应、抗Ca2+超载所致神经毒性、抗氧化应激损伤、调节中枢神经递质及其受体和抑制神经细胞凋亡等发挥保护中枢神经系统的作用。通过对这些芳香开窍中药的药理作用进行整合和总结，以期为该类药物治疗中枢神经系统疾病的进一步深入研究和临床应用提供参考依据。

Abstract: By summarizing the pharmacological effects of resuscitation-inducing aromatic herbs such as Moschus, Borneolum Syntheticum, Acori Tatarinowii Rhizoma, Styrax, Benzoinum and Chinese medicine formulas like cow-bezoar bolus for resurrection, heartprotecting musk pill and storax pill, it has been found that these herbs have an effect on central nervous system diseases such as ischemic stroke, Alzheimer's disease, depression, epilepsy and Parkinson's disease.Their mechanisms of protecting the central nervous system are mainly related to the regulation of permeability of the blood-brain barrier, inhibition of inflammatory response, resistance of neurotoxicity caused by Ca2+ overload, amelioration of oxidative stress damage, regulation of central neurotransmitters and their receptors, and inhibition of neuronal cell apoptosis.This paper attempts to provide some reference for future in-depth research and clinical application of such drugs in the treatment of central nervous system diseases through the integration and summary of the pharmacological effects of these resuscitation-inducing aromatic drugs.

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