首页 > 分享 > 多组学视角下植物精油抑菌机理的研究进展

多组学视角下植物精油抑菌机理的研究进展

花匠小妙招
2024-10-30 16:09

摘要： 近年来，植物精油的抑菌活性被广泛报道，并在食品、药品和化妆品行业得到广泛开发应用。国内外学者对其抑菌作用机理进行了研究，植物精油可以通过破坏细菌细胞膜、干扰细胞代谢活动、影响细菌核酸和蛋白质的合成等多种方式抑制微生物的生长，且植物精油成分复杂，具有多作用靶点、广谱抗菌性的特点。随着研究的不断深入，利用组学技术多层面深入解析抑菌机理已成为可能，开辟了植物精油抑菌机理研究的新视角。本文在介绍植物精油种类及抑菌活性的基础上，分别从转录组学、蛋白质组学、代谢组学及多组学联用技术角度系统性总结了植物精油抑菌机理的研究进展，并进行展望，旨在为抑菌剂多靶点抑菌机理解析与植物精油进一步在食品领域应用提供理论依据。

关键词: 转录组学；蛋白质组学；代谢组学；植物精油；抑菌机理

Abstract: In recent years, the antibacterial activity of plant essential oils has been extensively researched and applied in the food, drug, and cosmetics industries. Extensive research has discovered that plant essential oils can inhibit microbial growth in various ways such as disrupting the bacterial cell membrane, interfering with cellular metabolic activities, and influencing the synthesis of bacterial nucleic acids and proteins. Furthermore, plant essential oils exhibit a complex composition, with multiple target sites and broad-spectrum antibacterial properties. With the continuous advancement of research, omics technologies have made it possible to dissect the antibacterial mechanisms of plant essential oils. This article starts with an introduction to the classification and antibacterial activities of plant essential oils, and then summarizes recent progress in research on the antibacterial mechanisms of plant essential oils from the aspects of transcriptomics, proteomics, metabolomics, and multi-omics. Finally, this review provides an outlook on the future of this field, aiming to provide a theoretical foundation for understanding the multi-target antibacterial mechanisms of plant essential oils and for their application in the food industry.

Key words: transcriptomics; proteomics; metabolomics; plant essential oils; antibacterial mechanisms

中图分类号:

TS207.7